LC-MS/MS

We leverage our decades of experience in LC-MS/MS to successfully transition our competencies to peptides, proteins (intact and surrogate peptide quantification), monoclonal antibodies, and antibody-drug conjugates for both preclinical and clinical stages of drug development. We are adept at performing automated immunoaffinity sample preparation, and producing high-throughput assays with impressive sensitivity.

Our bioanalytical scientists and study experts also leverage innovative microsampling technology that allows low-volume blood draws to be taken from test subjects for analysis. We have developed specialized methods and workflows, including hybridization LC-MS assays, to take full advantage of current microsampling technology at the preclinical, clinical, and bioanalytical levels, and support the efficient advancement of your drug development program. Our microsampling services are fully customizable, available as a standalone, or as part of a complete development program.

Our capabilities are supported by over 30 LC-MS/MS instruments, including Sciex 5000, 5500, 6500+, and Selexion with Nexera UHPLCs. Our HRMS include the Sciex 5600, 6600, and ThermoFisher® Q-Exactive. We have micro-flow and nano-flow capabilities for the front end of our HRMS systems.