Overcome Matrix Shortage and Non-specific Binding Issues

Surrogate Cerebrospinal Fluid Method for ASO Quantitation

In this presentation, we identify a suitable surrogate matrix to overcome issues regarding the shortage of nonhuman primate matrices, and susceptibility to non-specific binding (inherent in the analysis of oligonucleotides), including the use of artificial cerebrospinal fluid.

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You may also be interested in the following:

• Webpages:
  • Oligonucleotide Capabilities
  • Bioanalytical Platforms
• eBook: Bioanalytical Developments for the Analysis of ASOs​​​​​​

Altasciences transforms the traditional outsourcing paradigm by simplifying and streamlining drug development solutions, whether for a single study or multiple programs, to offer an integrated/synchronized approach to CRO and CDMO services.